Zach Galifianakis and Amy Adams are in negotiations to star in the comedy Town House for Fox, a project originally conceived in 2007 that was interrupted by the writer’s strike at the end of the year with director John Carney (Once) attached.

From Variety, the story is loosely based on Tish Cohen’s novel of the same name about an agoraphobic (Galifianakis) and his son who live in an historic Boston townhouse inherited through his rock-star father. With monetary troubles, he’s forced to come to terms with life as he establishes a relationship with a call girl (Adams).

Doug Wright and Carney himself adapted the script, which will be produced by Ridley and Tony Scott through their production house Scott Free.

Amy Adams is one of my favorite actresses and almost criminally underutilized and under-appreciated. She gave the best performance in the otherwise stagey and overbearing Doubt, then was given the lesser of two roles in Nora Ephron’s Julie & Julia, which hit theaters late this summer. She does have performances in the upcoming romantic-comedy Leap Day and in David O. Russell’s The Fighter opposite Christian Bale and Mark Wahlberg, a project which once had David Aronofsky tapped to direct.

Zach Galifianakis, a key cast-member in the smash-hit The Hangover, will be Seth Rogen-busy over the next few years, including another odyssey with Bradley Cooper, Ed Helms and the “Hangover” boys.

Town House is set to start filming next summer.